Fox has found the female lead for its forthcoming series Best Medicine.
Abigail Spencer (Grey’s Anatomy, Rectify) will star opposite Josh Charles in the series, an adaptation of the long-running British dramedy Doc Martin. Spencer will play Louisa Glasson, a teacher in the small East Coast fishing village where Dr. Martin Best (Charles) relocates after leaving a decorated career as a surgeon in Boston.
Fox describes Best Medicine as an hour-long comedy following Martin, who abruptly leaves his post in Boston to work as a general practitioner in the town where he spent summers as a kid. “Unfortunately,” the show’s logline reads, “Martin’s blunt and borderline rude bedside manner rubs the quirky, needy locals the wrong way, especially local school teacher Louisa Glasson. However, tenacity is the creed of everyone in their small village, and the people who live there may be exactly what the doctor ordered.”
Production on Best Medicine is slated to begin later in the summer in upstate New York for a midseason premiere date on Fox’s 2025-26 schedule.
Fox Entertainment Studios is producing the series, which Fox will fully own. Liz Tuccillo executive produces with Ben Silverman, Howard T. Owens and Rodney Ferrell of Propagate Content and Doc Martin EPs Mark Crowdy and Philippa Braithwaite.
Spencer most recently had a guest-starring arc on ABC’s 911. Her TV credits also include Mad Men, Timeless, Extended Family and Suits. She is repped by UTA, Untitled Entertainment and Hansen Jacobsen.